ALS happens when specialized nerve cells called motor neurons break down and die — meaning the brain can no longer control muscles in the body. A team of Western University researchers led by Dr. Michael Strong has uncovered a potential path toward a cure for ALS. Strong’s team found that targeting an interaction between two proteins present in ALS-impacted nerve cells can halt or reverse the disease’s progression. The researchers discovered that when the two proteins interact with each other, the toxicity of the ALS-causing protein is removed, significantly reducing damage to the nerve cell and preventing its death. Now Strong’s team has set a goal to bring this potential treatment to human clinical trials within 5 years.